SIGNAL BREAKDOWN
IN DISEASE
we read or restore it?
Core Idea: Disease can be read as a loss of signal coherence—and health as its restoration.
We examine how diseases like cancer and neurodegeneration alter the flow and fidelity of physical signals—leading to systemic effects, including cognitive dysfunction. Our models bridge cancer biology and neuroscience to trace how local disruptions become global breakdowns in communication.
Key Directions:
• Biophotonic biomarkers of chemobrain: Identifying patterns of UPE and EEG disruption in cancer survivors experiencing cognitive decline.
• Cancer–brain communication: Developing neural–tumor co-culture models to trace how tumors alter electric, photonic, and vesicle-based signaling toward the CNS.
• Resilient signal buffering: Exploring the role of pigments like melanin in stabilizing bioenergetic and informational integrity under stress.