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REWRITING CELL FATE
WITH PHYSICAL INPUTS

Can applied signals serve as programmable languages to control morphogenesis,
repair, or disease regression?

Core Idea: Biophysical signals offer a programmable interface with biological systems—one that can be tuned, not just triggered.

We engineer biophysical interventions—light-based stimulation, magnetic field modulation, wearable electroceuticals—that can direct cell fate and tissue-level outcomes. These signals act as control inputs, allowing us to test and manipulate biological systems as dynamic information processors.

Key Directions:
• Limb and tissue regeneration: Building on our 2022 Science Advances study, we continue to develop wearable stimulation platforms that deliver spatiotemporally precise signals to drive regeneration.
• Cancer reprogramming: Applying biophysical inputs to shift malignant cells into dormant, apoptotic, or normalized states.
• Energetic resistance and fidelity: Modeling how tissues buffer and reshape incoming signals to maintain pattern integrity or fall into disease.